His roles include Ahmed Shah Massoud in the television mini-series The Path to 9/11 and smaller roles in the British television film Hannibal: Rome's Worst Nightmare and the series Feel the Force. In 2004, he played in the film Sky Captain and the World of Tomorrow. In the 2011 film Unknown, Hamada played a Saudi sheikh involved in an assassination attempt at a Berlin hotel and in funding biotechnological research.
In 2012, Hamada had a role in the Showtime series Homeland, playing a key member of a terrorist cell planning an attack on the United States. He most recently finished shooting a film The Situation where he played Zaid, an Iraqi Photographer. He portrayed "The Butcher" in the film American Sniper. He also lent his voice for the video game Disney Infinity 3.0.