Cesar Milstein

About Cesar Milstein

Who is it?: Biochemist, Immunologist
Birth Day: October 08, 1927
Birth Place: Bahía Blanca, Argentina, Argentine
Alma mater: University of Buenos Aires University of Cambridge
Known for: Receiving Nobel Prize "for theories concerning the specificity in development and control of the immune system and the discovery of the principle for production of monoclonal antibodies"
Spouse(s): Celia Prilleltensky (m. 1953)
Awards: FRS (1975) Nobel Prize in Physiology or Medicine (1984) Louisa Gross Horwitz Prize (1980) Wolf Prize in Medicine (1980) William Bate Hardy Prize (1981) Sir Hans Krebs Medal (1981) Franklin Medal (1982) Copley Medal (1989)
Fields: Biochemistry
Doctoral advisor: Stoppani

Cesar Milstein

Cesar Milstein was born on October 08, 1927 in Bahía Blanca, Argentina, Argentine, is Biochemist, Immunologist. Cesar Milstein was an Argentinian biochemist and immunologist who was bestowed with Nobel Prize in Physiology or Medicine in 1984 for his path-breaking work in the development of monoclonal antibodies. The work made him one of the most important scientists of the 20th century and his discovery one of the most important discoveries of the 20th century. A University of Buenos Aires alumnus, Milstein’s research in the field of immunology and immunogenetics began when he acted upon Frederick Sanger’s suggestion. Previously working on enzymology, Milstein shifted his focus to immunology. He collaborated with Georges Kohler to develop the hybridoma technique for the production of monoclonal antibodies. The duo pioneered the seminal technique for the production of monoclonal antibodies which created a rage in the scientific society. In 1975, they came up with a paper that published their discovery and later also displayed the clinical application. Apart from the discovery of monoclonal antibody, Milstein researched on the structure of antibodies and their genes, through the investigation of DNA and RNA. This research became fundamental for a better understanding of the functioning of the human immune system. In his lifetime, Milstein was showered with prestigious scientific awards and became a member of numerous scientific societies and institutions.
Cesar Milstein is a member of Scientists

Does Cesar Milstein Dead or Alive?

As per our current Database, Cesar Milstein has been died on 24 March 2002(2002-03-24) (aged 74)\nCambridge, England.

🎂 Cesar Milstein - Age, Bio, Faces and Birthday

When Cesar Milstein die, Cesar Milstein was 74 years old.

Popular As Cesar Milstein
Occupation Scientists
Age 74 years old
Zodiac Sign Scorpio
Born October 08, 1927 (Bahía Blanca, Argentina, Argentine)
Birthday October 08
Town/City Bahía Blanca, Argentina, Argentine
Nationality Argentine

🌙 Zodiac

Cesar Milstein’s zodiac sign is Scorpio. According to astrologers, Scorpio-born are passionate and assertive people. They are determined and decisive, and will research until they find out the truth. Scorpio is a great leader, always aware of the situation and also features prominently in resourcefulness. Scorpio is a Water sign and lives to experience and express emotions. Although emotions are very important for Scorpio, they manifest them differently than other water signs. In any case, you can be sure that the Scorpio will keep your secrets, whatever they may be.

🌙 Chinese Zodiac Signs

Cesar Milstein was born in the Year of the Rabbit. Those born under the Chinese Zodiac sign of the Rabbit enjoy being surrounded by family and friends. They’re popular, compassionate, sincere, and they like to avoid conflict and are sometimes seen as pushovers. Rabbits enjoy home and entertaining at home. Compatible with Goat or Pig.

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Famous Quotes:

Science will only fulfill its promises when the benefits are equally shared by the really poor of the world

— César Milstein, Un Fueguito

Awards and nominations:

Milstein was elected a Fellow of the Royal Society (FRS) in 1975, was a fellow of Darwin College, Cambridge from 1980 to 2002, awarded the Louisa Gross Horwitz Prize from Columbia University in 1980, won the Copley Medal in 1989, and became a Companion of Honour in 1995. In 1993 Konex Foundation from Argentina granted him the Diamond Konex Award, one of the most prestigious culture awards in Argentina, as the most important Scientist in the last decade in his country.

Biography/Timeline

1956

Milstein was born in Bahía Blanca, Argentina. His parents were Máxima (Vapniarsky) and Lázaro Milstein, a Jewish Ukrainian immigrant. He graduated from the University of Buenos Aires and obtained a PhD under Professor Stoppani (Professor of Biochemistry). In 1956 he received an award from the Sociedad Bioquímica Argentina for his work on kinetic studies with the enzyme aldehyde dehydrogenase. In 1958, funded by the British Council, he joined the Biochemistry Department at the University of Cambridge at Darwin College to work for a PhD under Malcolm Dixon on the mechanism of metal activation of the enzyme phosphoglucomutase. During this work he collaborated with Frederick Sanger whose group he joined with a short-term Medical Research Council appointment.

1975

Milstein was elected a Fellow of the Royal Society (FRS) in 1975, was a fellow of Darwin College, Cambridge from 1980 to 2002, awarded the Louisa Gross Horwitz Prize from Columbia University in 1980, won the Copley Medal in 1989, and became a Companion of Honour in 1995. In 1993 Konex Foundation from Argentina granted him the Diamond Konex Award, one of the most prestigious culture awards in Argentina, as the most important Scientist in the last decade in his country.

2002

Milstein died early on 24 March 2002 in Cambridge, England at age 74 as a result of a heart condition from which he had suffered for many years.

2014

Milstein himself made many major contributions to improvements and developments in monoclonal antibody technology—especially focusing on the use of monoclonal antibodies to provide markers that allow distinction between different cell types. In collaboration with Claudio Cuello, Milstein helped lay the foundation for the use of monoclonal antibodies as probes for the investigation of the pathological pathways in neurological disorders as well as many other diseases. Milstein and Cuello's work also enabled the use of monoclonal antibodies to enhance the power of immuno-based diagnostic tests. In addition Milstein foresaw the potential wealth of ligand-binding reagents that could result from applying recombinant DNA Technology to monoclonal antibodies and inspired the development of the field of antibody engineering which was to lead to safer and more powerful monoclonal antibodies for use as therapeutics.

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